50-21-5 MSDS - Lactic acid
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Lactic acid

Identification
Name Lactic acid
CAS Registry Number 50-21-5
Synonyms FEMA 2611;DL-ALPHA-HYDROXYPROPIONIC ACID;(+/-)-LACTIC ACID;LACTIC ACID;LACTIC ACID, RACEMIC;2-HYDROXYPROPIONIC ACID, RACEMIC;(+/-)-2-HYDROXYPROPIONIC ACID;2-HYDROXYPROPIONIC ACID
Molecular Structure Lactic acid   50-21-5
Molecular Formula C3H6O3
Molecular Weight 90.08
mp: 18℃
Hazard Codes: Details
Risk Statements: 38-41-34
Safety Statements: 26-39-45-36/37/39
RIDADR: 3265
Supplier
Lightchem Inc
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Wiki & MSDS
50-21-5.pdf
Lactic acid
Skeletal formula of L-lactic acid
L-Lactic acid
Ball-and-stick model of L-lactic acid
Names
Preferred IUPAC name
2-Hydroxypropanoic acid
Other names
Lactic acid
Milk acid
Identifiers
CAS Number
  • 50-21-5 YesY
  • 79-33-4 (L) YesY
  • 10326-41-7 (D) YesY
3D model (JSmol)
  • Interactive image
ChEBI
  • CHEBI:422 YesY
ChemSpider
  • 96860 YesY
ECHA InfoCard 100.000.017
E number E270 (preservatives)
IUPHAR/BPS
  • 2932
UNII
  • 33X04XA5AT N
Properties
Chemical formula
C3H6O3
Molar mass 90.08 g·mol−1
Melting point 53°C
Boiling point 122 °C (252 °F; 395 K) @ 15 mmHg
Acidity (pKa) 3.86,[1] 15.1[2]
Thermochemistry
Std enthalpy of
combustion (ΔcHo298)
1361.9 kJ/mol, 325.5 kcal/mol, 15.1 kJ/g, 3.61 kcal/g
Pharmacology
ATC code
G01AD01 (WHO) QP53AG02 (WHO)
Hazards
GHS pictograms GHS-pictogram-acid.svg[3]
GHS hazard statements
H315, H318[3]
GHS precautionary statements
P280, P305+351+338[3]
Related compounds
Other anions
lactate
Related carboxylic acids
acetic acid
glycolic acid
propionic acid
3-hydroxypropanoic acid
malonic acid
butyric acid
hydroxybutyric acid
Related compounds
1-propanol
2-propanol
propionaldehyde
acrolein
sodium lactate
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
N verify (what is YesYN ?)
Infobox references

Lactic acid is an organic compound with the formula CH3CH(OH)COOH. In its solid state, it is white and water-soluble. In its liquid state, it is clear. It is produced both naturally and synthetically. With a hydroxyl group adjacent to the carboxyl group, lactic acid is classified as an alpha-hydroxy acid (AHA). In the form of its conjugate base called lactate, it plays a role in several biochemical processes.

In solution, it can ionize a proton from the carboxyl group, producing the lactate ion CH
3
CH(OH)CO
2
. Compared to acetic acid, its pKa is 1 unit less, meaning lactic acid deprotonates ten times more easily than acetic acid does. This higher acidity is the consequence of the intramolecular hydrogen bonding between the α-hydroxyl and the carboxylate group.

Lactic acid is chiral, consisting of two optical isomers. One is known as L-(+)-lactic acid or (S)-lactic acid and the other, its mirror image, is D-(−)-lactic acid or (R)-lactic acid. A mixture of the two in equal amounts is called DL-lactic acid, or racemic lactic acid.

Lactic acid is hygroscopic. DL-lactic acid is miscible with water and with ethanol above its melting point which is around 17 or 18 °C. D-lactic acid and L-lactic acid have a higher melting point.

In animals, L-lactate is constantly produced from pyruvate via the enzyme lactate dehydrogenase (LDH) in a process of fermentation during normal metabolism and exercise. It does not increase in concentration until the rate of lactate production exceeds the rate of lactate removal, which is governed by a number of factors, including monocarboxylate transporters, concentration and isoform of LDH, and oxidative capacity of tissues. The concentration of blood lactate is usually 1–2 mmol/L at rest, but can rise to over 20 mmol/L during intense exertion[4] and as high as 25 mmol/L afterward.[5]

In industry, lactic acid fermentation is performed by lactic acid bacteria, which convert simple carbohydrates such as glucose, sucrose, or galactose to lactic acid. These bacteria can also grow in the mouth; the acid they produce is responsible for the tooth decay known as caries.[6][7][8][9]

In medicine, lactate is one of the main components of lactated Ringer's solution and Hartmann's solution. These intravenous fluids consist of sodium and potassium cations along with lactate and chloride anions in solution with distilled water, generally in concentrations isotonic with human blood. It is most commonly used for fluid resuscitation after blood loss due to trauma, surgery, or burns.


 







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